8/14/2023 0 Comments Protein turnover![]() ![]() The balance between acids and bases is measured using the pH scale. Protein plays a vital role in regulating the concentrations of acids and bases in your blood and other bodily fluids ( 16, 17). ACTH (adrenocorticotropic hormone): Stimulates the release of cortisol, a key factor in metabolism.Īmino acid chains of various lengths form protein and peptides, which make up several of your body’s hormones and transmit information between your cells, tissues and organs.ADH (antidiuretic hormone): Signals the kidneys to reabsorb water.hGH (human growth hormone): Stimulates the growth of various tissues, including bone.Glucagon: Signals the breakdown of stored glucose in the liver.Insulin: Signals the uptake of glucose or sugar into the cell.Protein and polypeptides make up most of your body’s hormones. Amines: These are made from the individual amino acids tryptophan or tyrosine, which help make hormones related to sleep and metabolism.The sex hormones, testosterone and estrogen, are steroid-based. Steroids: These are made from the fat cholesterol.Protein and peptides: These are made from chains of amino acids, ranging from a few to several hundred.Hormones can be grouped into three main categories ( 11): They’re made and secreted by endocrine tissues or glands and then transported in your blood to their target tissues or organs where they bind to protein receptors on the cell surface. As suggested in several publications, a bolus of 15-20 g protein (from skimmed milk or whey proteins) and carbohydrate (± 30 g maltodextrine) drinks is needed immediately after stopping exercise to stimulate muscle protein and tendon collagen turnover within 1 h.Some proteins are hormones, which are chemical messengers that aid communication between your cells, tissues and organs. Muscular activities promote a cascade of signals leading to the stimulation of eukaryotic initiation of myofibrillar protein synthesis. Nitrogen balance (difference between protein intake and protein degradation) for athletes is usually balanced when the intake of protein reaches 1.2 g Endurance exercise induces a greater oxidative capacity (enzymes) compared to resistance exercise, which induces fiber hypertrophy (myofibrils). Individuals who exercise respond differently when resistance and endurance types of contractions are compared. Strenuous exercise provokes increased proteolysis and decreased protein synthesis, the opposite occurring during the recovery period. There are different fractional synthesis rates in skeletal muscle and tendon tissues, but there is no major difference between collagen and myofibrillar protein synthesis. Stable isotopic tracers ((13)C-lysine, (15)N-glycine, ²H5-phenylalanine) and arteriovenous differences have been used in studies of skeletal muscle and collagen tissues under resting and exercise conditions. Noninvasive and invasive techniques have been applied to determine amino acid catabolism and muscle protein building at rest, during exercise and during the recovery period after a single experiment or training sessions. As for any cell or tissue, total muscle protein reflects a dynamic turnover between net protein synthesis and degradation. Skeletal muscle is the major deposit of protein molecules. ![]()
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8/14/2023 0 Comments Does aluminium rust![]() For a fresh surface-treated aluminum in the atmosphere is not contaminated, this threshold is about 66 % (drawing 1.2). This is because, that lacks moisture in low humidity, to create a continuous electrolytic film on the metal surface. There is a critical threshold for the relative humidity, below which aluminum and its alloys do not corrode. The critical relative humidityĪtmospheric corrosion of metals, including, aluminum, It occurs in thin films of moisture, which are arranged on the metal surface. Under these conditions at the metal surface can occur moisture condensation. moistening duration typically determined, as the time, during which the relative humidity exceeds 80 % and, in the same time, on the metal surface temperature is higher 0 oC. Lasting moisturizing called period, during which sufficient moisture on the surface of the metal to corrosion. Duration moisture and sulphate electrolyteĬorrosion metals outdoors depends on the so-called wetting length and chemical composition of the electrolyte surface. For a given level of humidity is the temperature, to which air must be cooled, to become saturated with moisture, and started her falling on nearby surfaces. ![]() The dew point is the temperature, at which moisture condensation will start. During the shower, it can reach 90-95 %, and during the tropical rains approach 100 %. In deserts and the arid zones of the relative humidity level seldom exceeds 10-20 %, whereas it is found mostly in temperate climates between 40 and 60 %. saturated with moisture, if the relative humidity of about 100 %.wet, if the relative humidity is higher 80 %.normal, if the relative humidity is between 50 to 60 %.dry, if the relative humidity is not more than 30 %.This ratio is expressed as a percentage.Īt normal room temperature, air is considered: Relative humidity - the ratio between the actual water vapor pressure and a maximum pressure of water vapor at a given temperature. Rain is one, but not the only factor, which determines the relative humidity. The rate of atmospheric corrosion is dependent on relative humidity, and not just on the number or intensity of rainfall in the area. These factors can also have the opposite effect: rain increases the humidity in the air., but also washes away dust, and corrosion products, which may reduce the corrosion rate relative humidity for instance, hung air contamination may reduce the critical value of the relative humidity, at which corrosion begins to develop. ![]()
8/14/2023 0 Comments Silk browser fire tv stick![]() ![]() It’s fast and familiar, so you don’t have to worry about learning the ins and outs of a new browser. ChromeĬhrome is another safe browser option. It’s easy to download from the Appstore and simple to navigate. Here are our top three Fire Stick browser recommendations. There are tons of browsers on the market, so selecting the right one for your Fire Stick can be difficult. Let’s learn how! How to Download Silk on a Fire Stick However, there is a way to sideload other browser apps on your Fire Stick using the Downloader app. How To Install a Web Browser on a Fire Stick?įollow the steps below to install Amazon Silk and other browsers on a Fire Stick.įire Stick’s natively supported browser is Silk, which was developed by Amazon. You can use the on-screen keyboard to type into the browser or attach a wireless keyboard via Bluetooth or a USB dongle. You can use browsers on your Fire Stick to open streaming sites, use search engines, and open links from Whatsapp, Skype, and other communication platforms. Yes, you can browse the web on a Fire Stick.īrowsing the web on a Fire Stick may look a little different than on a laptop, but it’s just as easy. Tips for Using a Browser on a Fire Stick.The Browser is not Compatible with Your Fire Stick.The Website is Not Compatible with Your Browser.What To Check When a Browser Is Not Working on a Fire Stick?. ![]() How to Download Other Browsers on a Fire Stick.How To Install a Web Browser on a Fire Stick?.Can You Browse the Web on a Fire Stick?. ![]() 8/14/2023 0 Comments Mint tim tams![]() ![]() ![]() Welcome to the party, Cream Wafer, Iced VoVo (shock horror!), Jam Tart and. What? How can some bikkies get a no-show? Well, they did. Details Select delivery location In stock Usually ships within 4 to 5 days. While the shortbread rated high, its plain sibling the Arrowroot was left in the dust, along with the basic Custard Cream.īut I'd like to add another unofficial tier to the ranking today, and that is the shocking '0' votes tier. 1195 (1.03 / Ounce) 9.70 delivery July 13 - August 3. Surprisingly, the Kingston (which I personally love) isn't a biscuit many poeple are into. READ MORE: Australia's favourite packet of chips is Smith's Original, exclusive Nine poll finds Monte Carlos were a take it or leave it. Sort by Arnotts Tim Tam Original 200g 8.97 + - Arnotts Tim Tam Double COAT 200g 8.97 + - Arnotts Tim Tam Chewy Caramel 175g 8. It consists of two malted biscuits separated by a light chocolate cream filling and coated in a thin layer of textured chocolate. They have their place, but they're not really that desperate addition to the shopping list. Tim Tam is a brand of chocolate biscuit made by the Australian biscuit company Arnott's. ![]() These guys rate a mention, but don't get our pulses racing or inspire us to pop the kettle on: chocolate digestive, Monte Carlo and gingernut. Oreos continue to be a favourite (iStock) Take it or leave it Layer in baking paper and seal in an airtight container for up to four weeks. But I feel perhaps these are eaten with a glass of milk. Shop Arnotts Tim Tam Chocolate Biscuits (Made in Australia) (Choc Mint) online at best prices at desertcart - the best international shopping platform in. There are plenty among us who can do without chocolate with their tea and bikkies. Not far behind - and in my opinion, quite surprisingly - was the plain and simple Scotch Finger or Shortbread. READ MORE: The best lockdown hot drinks, ranked from gold standard to 'nah' New TimTam flavours land pretty regularly and keep fans guessing (Nine) Fighting chance ![]() 8/14/2023 0 Comments Mcilpoog![]() ![]() ![]() It’s a nice touch that the tamper is held in place via a magnet on the underside of the control panel. Four portafilter baskets lets you switch between single and double shots, with single and double-walled options - should you use pre-ground coffee. Through this, you can adjust gradually until you find your perfect settings. You can set the coarseness of the grounds as well as the quantity to a precise degree via two separate dials. ![]() We love the customization this machine allows for. It’s quick to work too, although it will need 1-2 minutes to warm up at first. Not only that, it delivers too on test, we found this espresso machine performed consistently, delivering a high-quality flavor and texture of espresso complete with a thick layer of crema. This machine looks stunning on display with its stainless steel finish and visible pressure gauge. If you’re a true coffee connoisseur and customization is a top priority, we recommend the Breville Barista Express. Read our full Nespresso Vertuo Plus review. A nearby plant cost us a couple of capsules on test. And you will want to make sure nothing obstructs the lid when you load them. Remember that with the Vertuo Plus, you will need to purchase Vertuo capsules rather than the Classic capsules. The parts aren’t dishwasher-safe, which means you need to wash by hand when necessary, but there is a useful self-clean program to keep your machine in check. Plus, the water tank rotates, which allows you to adjust the design to suit your space. ![]() In terms of ease of use, there’s literally one button to control everything, so we found operation straightforward - even when we had to use it in the middle of the night. It’s also quick to brew your espresso or coffee despite the centrifugal process, with the entire process taking about two minutes from start to finish. True, there’s no built-in milk frother, but this design is often sold with a separate frother if milky drinks are more to your taste. You’ve got the option of producing a single or double espresso, or a 5 oz or 8 oz coffee, thanks to the large 60 oz water tank. So, you know it will give you the ideal brewing process whatever flavor of coffee you’re using. The machine is smart enough to adjust its temperature and speed based on the type of capsule you’re using as well - it does this by reading the barcode. And we couldn’t complain the espresso produced on test was smooth, with a delicious rich flavor and silky texture. This machine essentially spins the capsule as it brews, to help create an exceptional finish. It may be pricey compared to other capsule designs, but it’s a steal when lined up against espresso machines. Add to that, the Vertuo Plus offers centrifugal brewing technology, which is why it makes the list as one of the best espresso machines. Nespresso is one of the few capsule brands that’s able to do this. The Nespresso Vertuo Plus is an example of a rare capsule coffee machine design, in that it can achieve a high enough pressure and temperature to produce espresso. Here’s the best espresso machines you can buy right now based on our testing and reviews. Whether you’re looking for value for money, or need a compact design, we’ve got a recommendation. Consequently, we've formed a list of the best espresso machines you can buy. Where we tested the model ourselves, we brought it home and used it exactly as you would to find every strength and weakness behind the performance. We compared the specifications, as well as the limits of each design. We’ve scoured the marketplace and have put a range of models to the test to find those that offer the best performance. If you need a hand picking out the best espresso machine for your home, we can help. It needs to look good on top of this because it’s likely to be on display. Then there’s the design to consider, you want it to be intuitive and simple to use, with parts which are easy to clean. It should not taste overly burnt or bitter. Ideally, you want a shot of espresso to be balanced and smooth, with a thick layer of crema. First, the flavor of the espresso can vary between models. ![]() 8/14/2023 0 Comments Sumo deadlifts![]() ![]() Is Sumo Cheating?Īlright, let’s address this eternal debate, is the sumo deadlift…cheating? Many will argue that due to the smaller range of motion in a sumo stance vs. ![]() Holding the bar too wide can put extra tension on your lower back while a close grip can make it hard for you to balance the bar. A shoulder-width hand placement can prove to be the most optimal. Some people like to have a wider than shoulder width grip while the others like to keep their hands close to each other. The hand placement while performing the sumo deadlifts can be tricky. Some people make the mistake of overextending their lower back which can unlock their knees. Drive your hips into the bar to finish with a smooth lockout. If you’re a competitive powerlifter, you will need to stand with your knees and back locked out at the top of the movement. Make sure you push your knees out so they don’t come in the way of locking out your knees. You need to generate a lot of torque to crack the bar off the floor. Generate Torque and Push Your Hips ThroughĪs mentioned above, the sumo deadlifts are the hardest at the bottom of the movement. Turn your feet slightly out as doing this will make the lift shorter and easy. If you stand with your feet completely “ducked” out, the bar will be an inch in front of you which can make it harder to lift it off the ground, and put more pressure on your lower back. You want the barbell to be as close to you as possible while performing the sumo deadlifts, think of it as a razor that you are shaving your legs with. You neither want your feet to be pointing all the way out nor should they be pointing straight ahead. Point the Toes Outįeet placement is crucial to master the sumo deadlift, and it is where most people go wrong with the sumo deadlifts, and this can hinder the whole lift. Keeping your head and chest behind the bar at the start of the movement will help you in locking out your hips and knees at the top of the movement. Standing right behind the bar with your shins touching the barbell is the best position to start the lift. The proper knee sleeves can greatly enhance compression and support big lifts. On the other hand, some people stand on top of the bar which is not the best position to start either because the bar can bump into your knees on the concentric movement. ![]() Some people make the mistake of ducking out their toes, doing this automatically puts the barbell an inch in front of them, and this is not the spot to be. Take a stance which makes it easy for you to lift the weights off the ground. It is harder to move the weights off the floor than it is to lock our your hips and back at the top of the movement. The sumo deadlifts are harder at the bottom part of the movement. In reality, most people need a moderate sumo stance to lift heavy weights while maintaining the correct form, which reduces the risk of injury. Others say that the wider the stance, the less the lift actually counts. Some people have a false notion that the wider your sumo deadlift stance, the better it is. The stance will vary for people based on their height and mobility. There are no hard or fast rules when it comes to mastering the sumo deadlift stance, take your time to figure out what works for you. Sumo deadlifts are an advanced exercise and you need to perform them correctly to get the most out of them. Since you get into a squatter stance while lifting the weights, your lower body does more work in this variation as compared to the traditional deadlifts. The sumo deadlifts are great for people who have a stronger lower body. Sumo deadlifts have a less of a direct impact on your back, but utilize your hips, glutes and posterior chain more than the conventional stance.ĭue to the limited range of motion with the sumo deadlift, this variation of the exercise can actually enable you to lift heavier weights as compared to pulling with the conventional deadlift stance. There are many variations of the deadlifts which will keep you from getting bored of the exercise, such as conventional and sumo. Well, if you are performing an exercise incorrectly, it will almost certainly increase your risk for injury, which is why when it comes to movements like the deadlift, you need to take the time to master it. ![]() A lot of fitness “gurus” will say that deadlifts are pointless or will only put you at risk for injury, or that they’re too much on the joints. Master the Sumo Deadlifts with these Five Tipsĭeadlifts are no doubt one of the most brutal exercises, as they recruit muscles throughout your entire body. ![]() 8/14/2023 0 Comments Things to do in kansas city![]() While you’ll be safely strapped in with a harness, this isn’t one for the faint-hearted or anyone with a fear of heights! You also might get shown up by your children, who tend to love these treetop courses! GoApe in Kansas City is a lot of fun Ernie Miller Park and Centre The course takes you on an adrenaline-filled treetop adventure, navigating suspended bridges and flying through the air on zip lines. If you’re an adventurous sort, book in for a fun session at Go Ape in Swope Park. Kansas City Zoo is a popular place to visit with children Treetop Adventure Tour With so much to do, it’s a great place to visit for a family day out. This is also where you’ll find Kansas City Zoo, Lakeside Nature Centre, and even a treetop adventure park. Swope Park has beautiful rolling lawns with manicured gardens. How about a day out riding rollercoasters at Worlds of Fun in Kansas City? Swope ParkĪ few top outdoor activities surround Swope Park, making it a great base for adventuring. Inspired by Jules Verne’s ‘Around the World in Eighty Days’, you’ll definitely get your adrenaline fix riding rollercoasters across the globe before heading to the water park to cool down. You’ve got to visit the market in Kansas City Worlds of Funįun for kids and grown ups alike, a trip to this amusement park is one of the best things to do in Kansas City in the summer. ![]() If you’re all shopped out, sit back and people watch at one of the many charming cafes and eateries. Nibble on pastries as you walk around the market, looking at stalls selling flowers, gifts, and local goods. With over 150 years of history, it’s easy to spend hours at the well-established River Market. Shop until you drop at this open-area market. Whether you want to stroll around the neighbourhoods or go off on some exciting adventures, there are plenty of great outdoor activities in Kansas City. Kauffman Center for the Performing Artsġ6 Amazing Things To Do in Kansas City Outdoor Activities in Kansas City. ![]() Whether you’re planning a weekend away or a bigger trip around the region, it’s time to follow the yellow brick road to the most wonderful Kansas City tourist attractions! There are so many amazing things to do in Kansas City So, when you arrive in the city centre you could actually say “We’re not in Kansas anymore!” It actually lies on Missouri’s western edge, right on the border with Kansas State. If you’re not familiar with the geography of the region, you might think Kansas City is in Kansas State. View of Kansas City from the banks of the Missouri River When it comes to entertainment, you’ll love getting to know this city’s vibrant jazz scene and digging deep into the cuisine (get ready for some tasty BBQs!) Offering all of this and more, it’s no wonder Kansas City has become a must-visit destination. If you’re looking for authentic experiences, there’s an abundance of fun things to do in Kansas City. One day you could be flying through the trees on a GoApe course, the next you could be seeing some incredible contemporary art at one of the best galleries in the US. Kansas City is a unique destination with an atmosphere like no other. Kansas City is a ridiculously fun city.From visiting the River Market and exploring the American Jazz Museum, to amazing places to eat and drink, these are the best things to do in Kansas City. What are some fun things to do in Kansas City? The coldest month in Kansas City is January, and sometimes snowfall can begin as early as late October! Overall, though, winter in Kansas City is a gorgeous time, so get out and enjoy it.ģ. Kansas City sees about 18.2 inches of snow annually, which is ten inches less than the national average. Winter in Kansas City is a beautiful time of year, despite the cold! Daily highs tend to be in the mid-40s and lows rarely dip below 7 degrees, which is pretty chilly – but not as bad as it could be.
8/14/2023 0 Comments Convert powerpoint slide to jpg![]() You can get a free temporary license to use the API without the evaluation limitations. The following C# code example converts the PowerPoint presentation to PNG format. Convert the presentation to image using Convert() method.Load the presentation PPT/PPTX file using Converter class.The following steps guide how to convert the Powerpoint PPT or PPTX to PNG image format in C#. Let’s convert our slides into PNG in a similar way. One of the most in-use image formats is PNG. ![]() Convert Presentation to PNG Image using C# The following C# source code converts the PowerPoint presentation to JPG format.
8/14/2023 0 Comments Kite pharma el segundo address![]() The combined strength of Kite and Gilead allows us to remain innovative, agile, and ambitious in our mission to keep improving the lives of people with all types of cancer.įor more on Kite’s acquisition by Gilead Sciences in 2017, read the press release. As a vital part of Gilead - a founding member of the Foundation for the NIH’s Partnership for Accelerating Cancer Therapies - we are devoted to advancing the understanding of cell therapy as a transformational treatment option for cancer. Jun 2017 483 Kite Pharma, Jun 2017 119 - Available for instant download by Donald Ertel FDA, Michael Havert FDA, Arie Menachem FDA, Graeme Price FDA, Wei Wang FDA FDA investigators audited the Kite Pharma - El Segundo, CA, United States facility and issued inspectional observations (via FDA 483) on. Kite Pharmas ASCO ads aim to prep docs on CAR-T ahead of FDA approval. This forms the largest dedicated in-house cell therapy manufacturing network in the world, spanning process development, vector manufacturing. Confirmed: Gilead to acquire Kite Pharma for 11.9bn. The Oceanside site is part of Kite’s global commercial manufacturing network that includes facilities in El Segundo, California, Amsterdam, Netherlands, and a recently FDA-approved Maryland site. We are driven by our mission to bring these. Kite Pharma, and Dendreon Pharmaceuticals. Today, we are a leader in engineered T cell therapy, which has changed the paradigm of cancer treatment as one of the biggest breakthroughs in medicine since the introduction of combination chemotherapy more than 60 years ago. Since our acquisition by biopharma leader Gilead Sciences in October 2017, our combined strength has accelerated the advancement of our pipeline, including the launch of YESCARTA® (axicabtagene ciloleucel) and TECARTUS® (brexucabtagene autoleucel), and has expanded the impact of our strategic partnerships.Īs an independent operating company since 2019, we prioritize innovative R&D with the full resources, capabilities, and trust of Gilead. Kite has been at the forefront of cancer immunotherapy since 2009. Our Story A Singular Focus on Cell Therapyįounded in 2009 as a pioneer in cell therapy research, Kite’s leadership position in the immuno-oncology space was solidified with our research and development agreement with the National Cancer Institute in 2012 and when our commercial manufacturing site opened in El Segundo in 2016. Maintenance Manager Kite Pharma Aug 2021 - Present1 year 11 months United States Supervisor Facilities Kite Pharma Jun 2019 - Jun 20212 years 1 month El Segundo Sr Maintenance. ![]() 8/14/2023 0 Comments F1 timing app cracked![]() When the developers get all the bugs worked out it may well be an excellent app, but it’s a leap of faith at the moment.Ĭhoosing to cut back the free live timing page may make sense as a business decision, but failing to offer a corresponding paid version for desktop users doesn’t – and wouldn’t even if the paid add worked beautifully. Throughout the Australian Grand Prix weekend it was unusable, and on the infrequent occasions when it did run the data stream was usually well behind the free website timing screen. You get the full gamut of glitches: it fails to load, crashes mid-session, dumbly fails to respond to your taps and shows wildly incorrect information. I’m sure I would have enjoyed rummaging through the rich data on offer but I couldn’t, for the simple reason that the app is unbelievably buggy. The experience of using it is familiar from previous apps and does it a good job of presenting complicated and rapidly-changing data in an intelligible way. The paid version remains a one-year subscription. For your money you get much the same information as was available in last year’s app, including a live map of the circuit, detailed sector information and speed, gear and tyre data.Ī free offering remains, though as on the website you only get a basic leaderboard and text commentary. It’s now offered for a much more sensible £9.99 for the all-bells-and-whistles version. ![]() The new version, marketed by Formula One Digital Media instead of Soft Pauer, appeared with little fanfare shortly before the new season began but immediately distinguished itself with a substantial price cut. The 2013 edition was priced at an excessive £23.99 for a single season. ![]() Pricing has been a major area of complaint with this app in years past. But does the paid version offer a sufficient increase in functionality at a reasonable enough price to be worth it? Since the official Formula One app first went on sale it’s been a question of when rather than if the free version would be cut back to give viewers an incentive to buy. ![]() No sector times, no lap chart, no weather information – just a list of lap times and purple/green/white sector time indicator lights. The quieter sound of the new engines wasn’t the only cause for complaint for some during last week’s Australian Grand Prix.Īs the first race weekend of the season got underway many fans were more than a little disappointed to discover that the live timing page on the official F1 website had been stripped of most of its functionality. ![]() |
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